Published in Human Molecular Genetics
Proove Pain Perception accounted for 96% of the population and correlated with sensitivity (p<0.0004) to experimental pain.
Published in Journal of Addiction Research and Therapy
Proove Opioid Risk predicted patients with Opioid Use Disorder (OUD) with 96.7% accuracy (AUC) and 100% positive predictive value (PPV).
Published in Journal of Pain Research
Over 5,000 patients resulted in an average 50% pain reduction in 30 days (average reduction of 3.4 on a 0-10 numerical rating scale) using Proove insights.
Math is more stable and superior to science. Persian mathematician al-Khwārizmī, the father of algebra, was one of the most influential thinkers of all time. His last name is the root of the word “algorithm”, and his work in 820 AD, The Compendious Book on Calculation by Completion and Balancing, introduced the fundamentals of algebra which are still used today. A lot has changed in science since 820 AD when the “standard of care” in medicine drilled holes in people’s heads for headaches and barbers performed bloodletting and amputations, but mathematics has remained stable and far more accurate.
At Proove Genomics, we are committed to providing our patients with the highest quality of care and the most accurate diagnostic results possible.
According to the CDC, Chronic Pain affects 1 in 5 adults in the United States, over 50 million adults
According to the American Society of Addiction Medicine and NIH, 50% of Opioid Abuse is Due to Genetic Factors
With Chronic Pain being more prevalent and more expensive than Cancer, Diabetes, and Heart Disease combined, Proove Genomics is providing personalized pain medicine insights based on award-winning science and mathematics - far superior to the Wong-Baker "smiley face" to "frowny face" scale, the pain numerical rating scale, or questionnaires assessing risk.
With Proove Pain Sensitivity, Proove Genomics assesses various genotypic factors, as well as phenotypic factors, such as gender, ethnicity, and perceived stress using advanced mathematics to help clinicians classify patients' pain sensitivity levels. Knowing this information empowers clinicians to interpret a patient's self-reported numerical pain rating scale, as well as guide treatment and rehabilitation decisions.
With Proove Opioid Risk and Proove NSAID Risk, Proove Genomics assesses various genotypic factors, as well as phenotypic factors, such as a diagnosis of depression, personal and family histories, age and more using advanced mathematics to help clinicians classify patients' risk for medication-mediated side effects. Knowing this information empowers clinicians to safely prescribe medications to those patients who need it, and protect those patients who are at risk for serious adverse events.
With Proove Medication Insights, Proove Genomics assesses various genotypic factors, as well as phenotypic factors such as age, gender, and diet using advanced mathematics to help clinicians classify patients' precautions for certain medications based on FDA-approved package inserts. Since many pain patients are poly-pharmacy (taking more than one medication), clinical trials do not account for this reality, but Proove's testing does evaluate this real-life scenario.
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